ISSN 1662-4009 (online)

ey0017.14-11 | (1) | ESPEYB17

14.11. Increased weight loading reduces body weight and body fat in obese subjects - A proof of concept randomized clinical trial

C Ohlsson , E Gidestrand , J Bellman , C Larsson , V Palsdottir , D Hagg , PA Jansson , JO Jansson

To read the full abstract: EClinicalMedicine. 2020 Apr 30;22:100338. doi: 10.1016/j.eclinm.2020.100338.The gravitostat hypothesis was only recently proposed based on studies in rodents showing that the addition of external weights to the body limits the rate of weight gain, independent of leptin signalling. In rodents, this was achieved by inserting weighted balloons into the abdomina...